✦ LIBER ✦
D-penicillamine and gold salt treatments were complicated by myasthenia and pemphigus, respectively, in the same patient with rheumatoid arthritis
✍ Scribed by M. L. Ciompi; G. Marchetti; L. Bazzichi; L. Puccetti; M. Agelli
- Book ID
- 104713611
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 956 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0172-8172
No coin nor oath required. For personal study only.
✦ Synopsis
A 53-year-old woman with rheumatoid arthritis developed myasthenia gravis after 6 months of therapy with D-penicillamine. Nineteen months after D-penicillamine was discontinued and 12 months after the beginning of gold therapy, she developed pemphigus vulgaris. This is the first reported case of gold-induced pemphigus in rheumatoid arthritis. This study further underlines the complex interactions between the effects of treatment with sulfhydryl-disulfide exchange drugs and the altered immunological system of patients affected by rheumatoid arthritis.