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D-Lactate altered mitochondrial energy production in rat brain and heart but not liver

✍ Scribed by Binbing Ling; Fei Peng; Jane Alcorn; Katharina Lohmann; Brian Bandy; Gordon A Zello


Book ID
115022717
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
196 KB
Volume
9
Category
Article
ISSN
1743-7075

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The contribution of mitochondrial free radical production towards the initiation of lipid peroxidation (LPO) and functional injury in the post-ischemic heart is unclear. Using the isolated rat heart model, the effects of the uncoupler of mitochondrial oxidative phosphorylation dinitrophenol (DNP, 50