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d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia

✍ Scribed by Louise Verrall; Mary Walker; Nancy Rawlings; Isabel Benzel; James N. C. Kew; Paul J. Harrison; Philip W. J. Burnet

Book ID
109026113
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
669 KB
Volume
26
Category
Article
ISSN
0953-816X

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## Abstract D‐serine is an endogenous N‐methyl‐D‐aspartate (NMDA) receptor coagonist. It is synthesized from L‐serine by serine racemase (SRR), but many aspects of its metabolism remain unclear, especially in the forebrain, which lacks active D‐amino acid oxidase (DAO), the major D‐serine degradati