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Cytotoxicity of Selected Water-Soluble Polymer–cis-Diaminedichloroplatinum(II) Conjugates Against the Human HeLa Cancer Cell Line

✍ Scribed by Gregg Caldwell; Eberhard W. Neuse; Constance E. J. van Rensburg

Book ID
110409813
Publisher
Springer
Year
1997
Tongue
English
Weight
569 KB
Volume
7
Category
Article
ISSN
1053-0495

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In this screening study in vitro, two polymerconjugated, square-planar platinum(II) complexes bound to the carrier via a single primary amine ligand were tested for antineoplastic activity against the HeLa human cervical epithelioid carcinoma cell line. In the first of these conjugates, 1-Pt, the sp