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Cytotoxicity of monocrotaline in isolated rat hepatocytes: Effects of dithiothreitol and fructose

✍ Scribed by Marcos A. Maioli; Larissa C. Alves; Diego Perandin; Andréa F. Garcia; Flávia T.V. Pereira; Fábio E. Mingatto


Book ID
119377570
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
483 KB
Volume
57
Category
Article
ISSN
0041-0101

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## Abstract Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was to investigate the cy