Cytotoxicity of menadione and related quinones in freshly isolated rat hepatocytes: effects on thiol homeostasis and energy charge

Effect of oleate on the apparent Kmof mo

Effect of oleate on the apparent Kmof monoamine oxidase and the amount of membrane-bound hexokinase in isolated rat hepatocytes: Further evidence for the controlling role of the surface charge in hexokinase binding

✍ Lech Wojtczak; Volker Adams; Dieter Brdiczka 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 426 KB

Brief incubation of isolated rat hepatocytes in the presence of the oleate-bovine serum albumin complex resulted in a release to the cytosol of a portion of hexokinase (EC 2.7.1.1) normally bound to intracellular membranes. This was correlated with an increase of the negative surface potential of th