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Cytotoxicity of Bovine Seminal Ribonuclease: Monomer versus Dimer †

✍ Scribed by Lee, J. Eugene; Raines, Ronald T.

Book ID: 121258157
Publisher: American Chemical Society
Year: 2005
Tongue: English
Weight: 249 KB
Volume: 44
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi051668z

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## Abstract Bovine seminal ribonuclease (BS‐RNase) is a unique member of the pancreatic‐like ribonuclease superfamily. This enzyme exists as two conformational isomers with distinctive biological properties. The structure of the major isomer is characterized by the swapping of the N‐terminal segmen