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Cytotoxicity and DNA-damage in human lung epithelial cells exposed to respirable α-quartz

✍ Scribed by Carla Fanizza; Cinzia Lucia Ursini; Emilia Paba; Aureliano Ciervo; Arianna Di Francesco; Raffaele Maiello; Paolo De Simone; Delia Cavallo


Book ID
116919561
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
790 KB
Volume
21
Category
Article
ISSN
0887-2333

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## Abstract A causal pathway between quartz, silicosis and lung cancer has been postulated. The aim of our study was to assess cytotoxic effects induced in a human lung epithelial cell line (A549) by exposure to __α__‐quartz. Cells were exposed to respirable __α__‐quartz (SRM1878a, NIST) at 25, 50