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Cytotoxic Terpenoids from Turraea pubescens

✍ Scribed by Xiao-Ning Wang; Cheng-Qi Fan; Sheng Yin; Li-Ping Lin; Jian Ding; Jian-Min Yue

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
290 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Three new triterpenoids, turrapubesols A–C (1–3), and one new sesquiterpenoid, 1__Ξ±__,4__Ξ±__‐dihydroxyeudesman‐11‐ene (4), along with 12 known terpenoids were isolated from Turraea pubescens. The structures of the terpenoids were established on the basis of extensive spectroscopic analyses and by a chemical transformation. The previous assignment of the NMR data for guaidiol (5) was corrected. Some of the triterpenoids exhibited cytotoxicity against the P‐388 cell line.

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