Cytotoxic T lymphocyte antigen 4 polymorphisms and allergic asthma
β Scribed by A. J. M. Van oosterhout; D. T. Deurloo; P. C. Groot
- Book ID
- 108687113
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 164 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0954-7894
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Genetic susceptibility to type 1 autoimmune hepatitis is indicated by a preponderance of female subjects and strong associations with human leukocyte antigens (HLA) DRB1\*0301 and DRB1\*0401. The gene encoding cytotoxic T-lymphocyte antigen-4 (CTLA-4) on chromosome 2q33 may also influence autoimmuni
## Abstract ## BACKGROUND: Polymorphisms in the cytotoxic Tβlymphocyte antigen 4 (__CTLAβ4__) gene have been implicated in susceptibility to cancer, but the many published studies have reported inconclusive results. The objective of the current study was to conduct a metaβanalysis investigating th