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Cytotoxic Rhodium(III) and Iridium(III) Polypyridyl Complexes: Structure–Activity Relationships, Antileukemic Activity, and Apoptosis Induction

✍ Scribed by Mara Dobroschke; Yvonne Geldmacher; Ingo Ott; Melanie Harlos; Lisa Kater; Laura Wagner; Ronald Gust; William S. Sheldrick; Aram Prokop


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
523 KB
Volume
4
Category
Article
ISSN
1860-7179

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## Abstract Heating [Rh(dtbpy)(κ~2~‐__C,C′__‐CH~2~CMe~2~C~6~H~4~)(CH~2~CMe~2~Ph)] (1; dtbpy = 4,4′‐di‐__tert__‐butyl‐2,2′‐bipyridyl) in __p__‐xylene at 110 °C resulted in the formation of the 2‐__tert__‐butylphenyl complex [Rh(dtbpy)(κ~2~‐__C,C′__‐CH~2~CMe~2~C~6~H~4~)(C~6~H~4~__t__Bu‐2)] (3). Treat