Cytotoxic peptides: Naphthoquinonyl derivatives of luteinizing hormone-releasing hormone
โ Scribed by Shai Rahimipour; Lev Weiner; Prativa Bade Shrestha-Dawadi; Shmuel Bittner; Yitzhak Koch; Mati Fridkin
- Publisher
- Springer Netherlands
- Year
- 1998
- Tongue
- English
- Weight
- 514 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1573-3149
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Luteinizing hormone-releasing hormone (LHRH) neurons are unique among hypothalamic neurons in that they originate outside of the central nervous system. In most vertebrates, LHRH-immunoreactive (-ir) neurons are detected in the epithelium of the medial olfactory pit soon after its formation. The LHR
Studies on partially purified chicken hypothalamic luteinizing hormone releasing hormone (LHRH) utilizing chromatography, radioimmunoassay with region-specific antisera, enzymic inactivation, and chemical modification established that the peptide is structurally different from mammalian hypothalamic