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Cytotoxic Limonoids from Brazilian Melia azedarach.

✍ Scribed by Honglei Zhou; Atsuko Hamazaki; Jose Domingos Fontana; Hironobu Takahashi; Carolina Bueno Wandscheer; Yoshiyasu Fukuyama

Publisher
John Wiley and Sons
Year
2006
Weight
16 KB
Volume
37
Category
Article
ISSN
0931-7597

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Meliarachins A–K: Eleven Limonoids from
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## Abstract Eleven new limonoids, meliarachins A–K (**1**–**11**, resp.), together with five known ones, were isolated from the twigs and leaves of __Melia azedarach.__ The structures of the new compounds were elucidated on the basis of spectroscopic analysis. Compounds **4** and **8** exhibited mo

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## Abstract magnified image In order to find new and biologically active compounds, the constituents of the root bark of __Melia toosendan__ were investigated, and three new limonoids, 29‐[(2‐methylbutanoyl)oxy]‐2__Ξ±__‐hydroxyamoorastatone (**1**), 1,3‐__epi__‐29‐[(2‐methylbutanoyl)oxy]‐2__Ξ±__‐hyd