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Cytotoxic effect of menadione and sodium orthovanadate in combination on human glioma cells

✍ Scribed by Zahid M. Delwar, Dimitrios Avramidis, Elna Follin, Yan Hua, Åke Siden, Mabel Cruz, Kajsa M. Paulsson, Juan Sebastian Yakisich

Book ID
113064529
Publisher
Springer US
Year
2011
Tongue
English
Weight
524 KB
Volume
30
Category
Article
ISSN
0167-6997

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Arecoline, an active alkaloid of Areca catechu L., and sodium nitrite, a food additive, are highly cytotoxic and cytostatic on the Hep 2 cell line when administered in an acidic environment (pH 4.2) in the presence of S-9 mixture. Hep 2 cells (10(6)) were treated with either 0.145, 0.725 or 1.449 mM