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Cytotoxic Constituents of the Roots of Ekmanianthe l ongiflora

✍ Scribed by Peraza-Sánchez, Sergio R.; Chávez, Daniel; Chai, Hee-Byung; Shin, Young Geun; García, Ricardo; Mejía, Miliciades; Fairchild, Craig R.; Lane, Kate E.; Menendez, Ana T.; Farnsworth, Norman R.; Cordell, Geoffrey A.; Pezzuto, John M.; Kinghorn, A. Douglas


Book ID
120272888
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
72 KB
Volume
63
Category
Article
ISSN
0163-3864

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AbstractÐBioassay-guided phytochemical investigation of the roots of Exostema acuminatum (Rubiaceae) using human oral epidermoid carcinoma (KB) cells as a monitor, led to the isolation of two norditerpenoids, namely, (16R)-ent-16,17-dihydroxy-19-nor-kaur-4-en-3-one ( ) and (16S)-ent-16,17-dihydroxy-