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Cytotoxic activity of the third-generation bisphosphonate zoledronic acid in acute myeloid leukemia

✍ Scribed by Michael Fiegl; Matthias Juergens; Wolfgang Hiddemann; Jan Braess


Book ID
104040233
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
576 KB
Volume
31
Category
Article
ISSN
0145-2126

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The bisphosphonate zoledronic acid has a
✍ Andreas Guenther; Sharon Gordon; Markus Tiemann; Renate Burger; Frank Bakker; Jo πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 306 KB

## Abstract Nitrogen‐containing bisphosphonates (N‐BPs) are effective antiosteolytic agents in patients with multiple myeloma. Preclinical studies have also demonstrated that these agents have direct antitumor effects __in vitro__ and can reduce tumor burden in a variety of animal models, although