Cytotoxic Activities of Colombian Plant Extracts on Chinese Hamster Lung Fibroblasts

✍ Scribed by Adela López de Cerain; Roberto Pinzón; Jairo Calle; Ana Marín; Antonio Monge

• Book ID: 101286447
• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 173 KB
• Volume: 10
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199608)10:5<431::aid-ptr863>3.0.co;2-m

✦ Synopsis

Fifty-one crude extracts from 31 Colombian plants used in traditional medicine have been screened for cytotoxicity in a MTT assay with V79 cells. Eleven extracts (21%) were active, showing a survival percentage below 20% with respect to the controls. The most active were ethanol and dichloromethane extracts from Acnistus arborescens leaves. The IC,, values obtained (6 and 11 & n L ) encourage a more in depth investigation.