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Cytostatic activity of new synthetic anti-tumor aza-alkyllysophospholipids

✍ Scribed by Carole Sidoti; Paola Principe; Benedicte Vandamme; Colette Broquet; Pierre Braquet

Publisher
John Wiley and Sons
Year
1992
Tongue
French
Weight
543 KB
Volume
51
Category
Article
ISSN
0020-7136

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✦ Synopsis

Alkyllysophospholipids are analogues of the naturally occurring 2-lysophosphatidylcholine which have been reported to have selective in vitrolin vivo anti-tumor activity. Their antiproliferative effect has been found against a variety of animal and human tumor cell lines. We have characterized the cytostatic activity of 2 newly synthetized aza-alkyllysophospholipids (AALPs), the BN52205 and the BN522 I I, on a human tumor

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