Cytostatic activity against HEp-2 cells of methanol extracts from Viscum cruciatum Sieber parasitic on Crataegus monogyna Jacq. and two isolated principles

✍ Scribed by M. A. Gómez; M. T. Sáenz; M. D. García; M. C. Ahumada; R. De La Puerta

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 84 KB
• Volume: 11
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199705)11:3<240::aid-ptr54>3.0.co;2-k

✦ Synopsis

We have determined the cytostatic activity in vitro against HEp-2 cells of methanol extracts from V. cruciatum Sieber (Viscaceae) parasitic on C. monogyna Jacq. (Rosaceae), C. monogyna parasitized and C. monogyna. nonparasitized. The methanol extracts assayed exhibited a moderate degree of growth inhibition compared with the values obtained with the 6-mercaptopurine (solution used as a positive control). Hyperoside from C. monogyna showed only a low degree of growth inhibition. However, ␤-amyrin acetate, from V. cruciatum, exhibited a high degree of growth inhibition compared with the values obtained with the solution used as a positive control.