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Cytostasis of lymphoma cells in suspension: Probable non-thymic origin of the cytostatic lymphoid cells in mice bearing MSV-induced tumors

✍ Scribed by A. Senik; L. De Giorgi; E. Gomard; J. P. Levy


Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
355 KB
Volume
14
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

Lymphoid cell suspensions of MSV‐tumor‐bearing mice were studied in the cytostasis assay (CA) against syngeneic lymphoma cells in suspension. Pretreatment by anti‐θ serum and complement, carbonyl iron and a magnet, or filtration through antiimmunoglobulin‐coated glass bead columns shows that macrophages are probably the main effector cells of the cytostatic anti‐tumor effect demonstrated by the CA, which further illustrates the diversity of the anti‐tumor immune response in the MSV system.