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Cytosolic Ca2+Gradients in Pancreatic Islet-Cells Stimulated by Glucose and Carbachol

✍ Scribed by Franz Martı́n; Juan Ribas; Bernat Soria

Book ID
115580410
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
229 KB
Volume
235
Category
Article
ISSN
0006-291X

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✍ Erik Gylfe 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 545 KB

The effect of carbachol on the cytoplasmic Ca2+ concentration [( Ca2+]i) was studied in insulin-releasing mouse pancreatic beta cells hyperpolarized by the K(+)-channel-activating agent diazoxide. By mobilizing intracellular Ca2+, carbachol induced an initial [Ca2+]i transient, which was more than t