Osmotic forces are not critical for Ca2+
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Sally Jo Stoehr; James E. Smolen
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Article
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1988
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John Wiley and Sons
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English
β 948 KB
In order to examine the role of osmotic forces in degranulation, the effects of solutes and osmolality on granule secretion were explored using both FMLPstimulated, intact neutrophils and Ca2+-stimulated, permeabilized cells. We employed a HEPES-based buffer system which was supplemented with: a) pe