## Abstract Statin treatment is proposed to be a new potential therapy for multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. The effects of statin treatment on brain cells, however, are hardly understood. We therefore evaluated the effects of simvastatin
Cytoskeleton: JMY: actin up in cell motility
β Scribed by Wrighton, Katharine H.
- Book ID
- 109959164
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 164 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm2678
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The machinery for cell locomotion is based in a network of polymerized actin filaments supporting the peripheral cytoplasm. This network or 'gel' consists of actin filaments in a variety of configurations, including cables, loose bundles, and branching arrays; all formed by the interaction of actin-
Motility is an essential and varied aspect of life. From the locomotion of whole organisms to intracellular movements, the complexity as well as the beauty of the motility can be observed in moving images. Observation of the motility is the first step in understanding the bases for the diverse metho