✦ LIBER ✦

Cytosine deaminase/5-fluorocytosine gene therapy and Apo2L/TRAIL cooperate to kill TRAIL-resistant tumor cells

✍ Scribed by Wei, J; Wahl, J; Knauss, H; Zeller, S; Jarmy, G; Fitze, G; Debatin, K-M; Beltinger, C

Book ID: 110019449
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 287 KB
Volume: 14
Category: Article
ISSN: 0929-1903
DOI: 10.1038/sj.cgt.7701051

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Proteasome inhibitor MG132 upregulates d

Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells

✍ He, Qin; Huang, Ying; Sheikh, M Saeed 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 208 KB

Hypoxia response element-driven cytosine

Hypoxia response element-driven cytosine deaminase/5-fluorocytosine gene therapy system: a highly effective approach to overcome the dynamics of tumour hypoxia and enhance the radiosensitivity of prostate cancer cells in vitro

✍ Laure Marignol; Ruth Foley; Thomas D. Southgate; Mary Coffey; Donal Hollywood; M 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 289 KB

## Abstract ## Background We proposed to exploit hypoxia‐inducible factor (HIF)‐1α overexpression in prostate tumours and use this transcriptional machinery to control the expression of the suicide gene cytosine deaminase (CD) through binding of HIF‐1α to arrangements of hypoxia response elements.