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Cytosine-5-methyltransferases add aldehydes to DNA

✍ Scribed by Liutkevičiūtė, Zita; Lukinavičius, Gražvydas; Masevičius, Viktoras; Daujotytė, Dalia; Klimašauskas, Saulius


Book ID
109913223
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
240 KB
Volume
5
Category
Article
ISSN
1552-4450

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Cytosine-5-methyltransferases add aldehy
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## Abstract We have developed a facile procedure for the purification of DNA methyltransferase activity from human placenta. The procedure avoids the isolation of nuclei and the dialysis and chromatography of large volumes. A purification of 38,000‐fold from the whole cell extract has been achieved