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Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases

✍ Scribed by Chen, Xiang-Jun; Xu, Huan; Cooper, Helen M.; Liu, Yaobo

Book ID
121648199
Publisher
Science in China Press (SCP)
Year
2014
Tongue
English
Weight
541 KB
Volume
57
Category
Article
ISSN
1674-7305

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## Abstract The nucleolus may represent a key stress response organelle in the nucleus following proteotoxic stress by serving as a platform for protein aggregates. Aggregation of proteins often results from insufficient protein degradation by the ubiquitin‐proteasome system (UPS), occurring in inc