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Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase ‘Synoviolin’

✍ Scribed by Yamasaki, Satoshi; Yagishita, Naoko; Sasaki, Takeshi; Nakazawa, Minako; Kato, Yukihiro; Yamadera, Tadayuki; Bae, Eunkyung; Toriyama, Sayumi; Ikeda, Rie; Zhang, Lei


Book ID
110031870
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
313 KB
Volume
26
Category
Article
ISSN
0261-4189

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✍ Jun Tashiro; Seiji Kikuchi; Kazuyoshi Shinpo; Riichiro Kishimoto; Sachiko Tsuji; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 985 KB

## Abstract The endoplasmic reticulum (ER) is important for maintaining the quality of cellular proteins. Various stimuli can disrupt ER homeostasis and cause the accumulation of unfolded or misfolded proteins, i.e., a state of ER stress. Recently, ER stress has been reported to play an important r