Cytophotometric assessment of phagocytosis and pinocytosis on single resident and exudate murine peritoneal macrophages
β Scribed by J. M. Papadimitriou; Ivonne van Bruggen
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 325 KB
- Volume
- 137
- Category
- Article
- ISSN
- 0022-3417
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β¦ Synopsis
Abstract
Computerised scanning cytophotometry was used to evaluate the phagocytic and pinocytic performance of single resident and exudate macrophages. The results indicate that both receptor mediated phagocytosis and fluid phase pinocytosis are more efficiently performed by activated than resident murine peritoneal macrophages. Exudate macrophages phagocytise at approximately twice the rate of resident macrophages while pinocytosis is five times more prominent in exudate than in resident macrophages. The results are consistent with other published investigations and in addition reflect individual cellular variation in macrophage populations.
π SIMILAR VOLUMES
## Abstract The relative magnitude of the negative charge per unit area on the surface of resident and exudate macrophages as well as multinucleate giant cells was assessed by cytophotometric and ultrastructural techniques. The results indicate that the surface of resident macrophages possesses a h