## Background: Papillary thyroid carcinoma is the most common malignant neoplasm of the thyroid gland, and fine-needle aspiration biopsy (fnab) often is the initial diagnostic method used in its detection. prior studies have shown that immunohistochemical staining for various cytokeratins in genera
Cytopathology of papillary oncocytic carcinoma of the thyroid in fine-needle aspiration biopsy
โ Scribed by Gia-Khanh Nguyen
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 183 KB
- Volume
- 23
- Category
- Article
- ISSN
- 8755-1039
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โฆ Synopsis
The fine-needle aspirates from two histologically, immunohistochemically, and ultrastructurally confirmed encapsulated papillary oncocytic carcinoma of the thyroid revealed large and small papillary tumor tissue fragments consisting of fibrovascular cores covered with polygonal cells showing abundant and granular cytoplasm and small, oval nuclei. Abundant single and loosely clustered tumor cells with similar cytologic features were also present. Nuclear pleomorphism, irregular nuclear contours, nuclear grooves, and intranuclear cytoplasmic inclusions were not observed in any tumor cells. The two patients were alive and well and showed no evidence of tumor recurrence and/or metastatic disease 6 and 8 years after their thyroid surgeries, respectively.
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