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Cytomorphologic features of the plasmacytoid variant of urothelial carcinoma: A case report

✍ Scribed by Sean K. Lau

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
336 KB
Volume
37
Category
Article
ISSN
8755-1039

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✦ Synopsis

Abstract

The plasmacytoid variant of urothelial carcinoma is an uncommon form of urothelial carcinoma with a distinctive histologic appearance. Descriptions of the cytologic features of this particular type of urothelial carcinoma in urinary specimens are limited. The present report details the urinary cytomorphologic findings of a plasmacytoid urothelial carcinoma occurring in the urinary bladder of a 66‐year‐old male. Bladder washings showed the presence of scattered dyscohesive cells with a plasmacytoid appearance characterized by abundant amounts of cytoplasm, eccentrically located nuclei, and inconspicuous nucleoli. The diagnosis of plasmacytoid urothelial carcinoma was confirmed upon histologic examination of a concurrently performed transurethral resection specimen, with immunohistochemical studies supporting this interpretation. Although rare, the plasmacytoid variant of urothelial carcinoma should be a diagnostic consideration when atypical cells with plasmacytoid features are encountered in a urinary specimen. Diagn. Cytopathol. 2009. Β© 2009 Wiley‐Liss, Inc.

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