Cytomegalovirus retinitis in patients with AIDS in Europe
β Scribed by M. Burke; I. Yust; C. Katlama; N. Vardinon; N. Clumeck; A. J. Pinching; B. Ledergerber; J. M. Gatell; A. Chiesi; S. E. Barton; J. D. Lundgren; C. Pedersen
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 674 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0934-9723
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Treatment of retinitis by cytomegalovirus (CMV) in AIDS patients requires frequent repetitive iniections of intravitreal ganciclovir (GCV). This study was undertaken to establish experimentally whether the intravitreal application of liposomally-entrapped GCV could prolong intraocular therapeutic le
## Abstract Nine patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus (CMV) retinitis on maintenance therapy with ganciclovir: 9(1,3βdihydroxyβ2βpropoxymethyl) guanine (DHPG) at high dose (30 mg/kg/week) or low dose (20 mg/kg/week) were tested every 1β2 weeks for CMV isolatio