Cytolytic human T-Cell clones expressing epstein-barr virus specificity and HLA restriction
✍ Scribed by Sethi, K.K.; Sethi, I.; Sethi, H.
- Book ID
- 123198763
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 900 KB
- Volume
- 160
- Category
- Article
- ISSN
- 0171-2985
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## Abstract Gp350, a late Epstein‐Barr‐virus (EBV) glycoprotein expressed on both the envelope of viral particles and EBV‐producing cells, is also the candidate for the development of an anti‐EBV subunit vaccine. This glycoprotein is thought to play an important role in anti‐EBV immunity. However,
Helper T-cell clones were generated by stimulation with autologous or allogeneic lymphoblastoid B cells (B-LCL) transformed by the Epstein-Barr virus (EBV). Some of these T-cell clones were allo-reactive and others were specific to EBV-transformed B-LCL. Helper T-cell clones specific to EBV-transfor