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Cytological and cytogenetical studies on brain tumors

โœ Scribed by H. Zankl; A. F. Weiss; K. D. Zang

Publisher
Springer
Year
1975
Tongue
English
Weight
361 KB
Volume
30
Category
Article
ISSN
0340-6717

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โœฆ Synopsis

The recently detected reciprocal translocations in chronic myeloic leucemia (CML) and Burkitt's lymphoma (BL) made it necessary to clarify if meningiomas really show the described monosomy 22 or also a translocation. In 10 out of 12 meningiomas a total or partial translocation of the missing chromosome 22 to another chromosome could be ruled out by fluorescence banding analysis. Two meningiomas showed marker chromosomes of such a complex composition that it was impossible to decide if a 22 translocation was present or not. From these results it was concluded that meningioma cells, in contrast to CML and BL, show almost regularly a loss of a definitive part of their genome.

๐Ÿ“œ SIMILAR VOLUMES

Cytogenetic studies of human brain tumor
Cytogenetic studies of human brain tumors and their clinical significance
โœ Frederick R Latimer; Abdul A AlSaadi; Thomas O Robbins ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer US ๐ŸŒ English โš– 315 KB

Four medulloblastomas were studied cytogenetically with clinical follow-up of the patients. Three of these lesions were diploid and the patients manifested no recurrence at 40, 37 and 36 months respectively. The remaining tumor was aneuploid with 52 chromosomes and the patient expired of the medullo