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Cytologic features of villoglandular adenocarcinoma of the uterine cervix

✍ Scribed by Chang, Wei Chi ;Matisic, Jasenka P. ;Zhou, Chen ;Thomson, Thomas ;Clement, Philip B. ;Hayes, Malcolm M. M.


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
767 KB
Volume
87
Category
Article
ISSN
0008-543X

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✦ Synopsis


BACKGROUND.

To the authors' knowledge, the cytologic features of villoglandular adenocarcinoma (VGC) have been described in very few publications. The malignant cells are difficult to separate from reactive glandular cells and the majority of VGCs are missed on screening cytology.

METHODS.

The cytologic findings of a retrospective study of four cases of pure VGC are described and are contrasted with those of papillary serous adenocarcinoma and typical mucinous endocervical adenocarcinoma with a focal component of VGC.

CONCLUSIONS.

The diagnosis of VGC on cytology smears often is missed. Papillary fragments, nuclear crowding, and subtle atypia may suggest the diagnosis. Cancer


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