Cytologic features of pulmonary malakoplakia related to Rhodococcus equi in an immunocompromised host

✍ Scribed by K.H. van Hoeven; D.B. Dookhan; Robert O. Petersen

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 529 KB
• Volume: 15
• Category: Article
• ISSN: 8755-1039
• DOI: 10.1002/(sici)1097-0339(199611)15:4<325::aid-dc14>3.0.co;2-q

✦ Synopsis

Cytologic features are described in bronchial brushings of a large cavitary lung mass from an immunosuppressedpatient who had undergone liver transplantation, Scattered histiocytes with abundant eosinophilic, vacuolated cytoplasm were noted in a background of bronchial cells. Within approximately one fourth of the histiocytes, targetoid intracytoplasmic inclusions were present, consistent with Michaelis-Gutmann bodies. They were diffusely positive by histochemical staining with von Kossa, Gomori methenamine silver, and periodic acid-Schif stains, and focally positive with Prussian blue stain, Cultures of the abscess yielded Rhodococcus equi. The characteristic microscopic features of pulmonary malakoplakia can be discerned in bronchial brushings

, and should be sought, particularly in immunocompromised patients. Diagn Cytopathol 1996; 15: 325-328. O 19% Wiley-Lis~. IUC.