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Cytokines Required for Induction of Histocompatibility Leukocyte Antigen-class I-restricted and Tumor-specific Cytotoxic T Lymphocytes by a SART1-derived Peptide

✍ Scribed by Matsunaga, Kazuko ;Nakao, Masanobu ;Masuoka, Kazuhiro ;Inoue, Yoshiko ;Gouhara, Rumi ;Imaizumi, Toshihiro ;Nishizaka, Shinya ;Itoh, Kyogo


Book ID
108581814
Publisher
Wiley (Blackwell Publishing)
Year
1999
Tongue
English
Weight
150 KB
Volume
90
Category
Article
ISSN
0910-5050

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We have described the SART-1 gene-encoding peptides recognized by HLA-A2601-restricted and tumor-specific cytotoxic T lymphocytes (CTLs). We now have investigated whether SART-1 encodes peptides capable of inducing the HLA-A24-restricted CTLs. Among the 18 different peptides with HLA-A24-binding mot

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Two types of biochemically defined class I major histocompatibility complex (MHC) antigens are found in the rat, RT1.A antigens that are ubiquitously expressed and RT1.C antigens which so far are detectable only on certain cell types, notably B and T lymphocytes. It is shown that the cytotoxic T lym