Cytokines involved in the progression of multiple myeloma
โ Scribed by F. MERICO; L. BERGUI; M. G. GREGORETTI; P. GHIA; G. AIMO; I. J. D. LINDLEY; F. CALIGARIS-CAPPIO
- Book ID
- 108698466
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 464 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0009-9104
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## Abstract Multiple myeloma is recognized as a neoplasm of phenotypically mature plasma cells which produces a variety of clinical symptoms related both to tumour infiltration of the bone marrow and cytokine production. The latter results in bone disease and a complex interactive network between p
One hundred twenty-eight records of patients with multiple myeloma were reviewed to assess the incidence and manifestations of liver involvement. Histologic study of the liver was available in 21 patients. Diffuse infiltration of the liver by plasma cells was observed in 10 patients, myeloid metapla