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Cytokines and their antagonists as therapeutic agents

✍ Scribed by S. C. Gilman; E. Mochan


Publisher
SP Birkhäuser Verlag Basel
Year
1988
Tongue
English
Weight
215 KB
Volume
25
Category
Article
ISSN
1420-908X

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## Abstract The chemokine receptor CXCR4 possesses multiple critical functions in normal and pathologic physiology. CXCR4 is a G‐protein‐coupled receptor that transduces signals of its endogenous ligand, the chemokine CXCL12 (stromal cell‐derived factor‐1, SDF‐1). The interaction between CXCL12 and