Cytokine-specific induction of the TGF-β inducible early gene (TIEG): Regulation by specific members of the TGF-β family

Cell type-specific regulation of the TGF

Cell type-specific regulation of the TGF-β-responsive α2(I) collagen gene by CpG methylation

✍ Kenichi Yamane; Hiroyuki Suzuki; Hironobu Ihn; Mitsuyasu Kato; Hirohide Yoshikaw 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB

## Abstract The α2(I) collagen gene shows cell type‐specific expression, however, the mechanism behind this specificity remains to be determined. We demonstrate here that transforming growth factor‐beta (TGF‐β)‐mediated induction of α2(I) collagen gene is regulated by DNA methylation in a cell type