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Cytokine response to endotoxin in individuals heterozygous for the Δ32 mutation of chemokine receptor CCR5

✍ Scribed by Michael Heesen; Emile F Schippers; Brunhilde Bloemeke; Dagmar Kunz; Jaap T van Dissel


Book ID
117700635
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
92 KB
Volume
21
Category
Article
ISSN
1043-4666

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A survey for 32 nucleotide deletion in t
✍ Voevodin, Alexander; Samilchuk, Elena; Dashti, Suhaila 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB 👁 1 views

The 32 nucleotide deletion in the CCR-5 chemokine receptor gene referred to as ⌬ccr-5 has been shown to confer resistance to HIV-1. Using PCR, 1,105 human subjects and 33 common chimpanzees were genotyped attributing them to one of the three possible genotypes: wild-type homozygote (w/w); ⌬ccr-5 hom