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Cytokine Regulation and the Signaling Mechanism of Osteoclast Inhibitory Peptide-1 (OIP-1/hSca) to Inhibit Osteoclast Formation

✍ Scribed by Masanori Koide; Hidefumi Maeda; Jennifer L Roccisana; Noriaki Kawanabe; Sakamuri V Reddy

Book ID
111487279
Publisher
American Society for Bone and Mineral Research
Year
2003
Tongue
English
Weight
437 KB
Volume
18
Category
Article
ISSN
0884-0431

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## Abstract Immune cell products such as interferon (IFN)‐γ and interleukin (IL)‐12 are potent inhibitors of osteoclast formation. We previously characterized the human osteoclast inhibitory peptide‐1 (OIP‐1/hSca), a Ly‐6 gene family member and showed IFN‐γ modulation of OIP‐1 expression in bone ma