Cytokine profile defines different responses to interferon-alpha treatment in chronic hepatitis C virus infection
โ Scribed by Antonietta Giannattasio; Munter Hussain; Giorgina Mieli-Vergani; Raffaele Iorio; Angela Vegnente; Diego Vergani
- Book ID
- 119228331
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 55 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1590-8658
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๐ SIMILAR VOLUMES
## Abstract Hepatitis C virus (HCV) replication was assessed before and during alphaโinterferon (IFN) treatment in 22 antiโHCV positive patients with posttransfusion or sporadic chronic hepatitis (CH). Eleven patients were โrespondersโ and 11 patients โnonโrespondersโ to IFN. Thirteen antiโHCV nega
Combination treatment with pegylated-interferon-alpha (PEG IFN-โฃ) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may