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Cytokine production by skin-derived mast cells: Endogenous proteases responsible for degradation of cytokines

✍ Scribed by Zhao, W.; Oskeritzian, C.A.; Pozez, A.L.; Schwartz, L.B.


Book ID
119275707
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
30 KB
Volume
115
Category
Article
ISSN
1097-6825

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Endothelin-1 (ET-1), originally described as a vasoconstrictor, is now known to be involved in pathogenesis of various disorders including vascular, inflammatory, and fibrotic diseases. Recent studies suggest that mast cells are also involved in the same pathological conditions. In this study, we te