Cytokine messenger rna expression in the labial salivary glands of patients with Sjögren's syndrome
✍ Scribed by Yukiko Ohyama; Seiji Nakamura; Goro Matsuzaki; Masanori Shinohara; Akiko Hiroki; Takao Fujimura; Akira Yamada; Kyogo Itoh; Kikuo Nomoto
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 899 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To clarify the molecular mechanisms of Sjögren's syndrome (SS), we analyzed the functional role of the STAT‐1 gene, one of the interferon‐γ (IFNγ)–inducible genes, in labial salivary glands (LSGs) from SS patients. ## Methods The expression of STAT‐1 messenger RNA (mRNA)
Objective. Salivary glands of patients with Sjogren's syndrome (SS) have been shown to be a site of antias-B/La antibody production. The present study investigated differences in the localization of the SS-B/La antigen in labial salivary gland (LSG) tissue between SS and non-SS patients, which may e