Cytokine Levels in Serum of Patients with Juvenile Rheumatoid Arthritis
✍ Scribed by M. Yılmaz; S. G. Kendirli; D. Altıntas; G. Bing&0uml;l; B. Antmen
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 84 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0770-3198
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Twenty-three children with destructive polyarticular juvenile rheumatoid arthritis (JRA) were treated for 0 . 5 4 3 years (median 1.6 years) with weekly doses of methotrexate (MTX) (0.11-0.6 mg/kg/week). Serum levels of MTX at 1 hour and at 24 hours after drug administration were obtained at each do
Objective. To examine the usefulness of determining extended serum cytokine profiles in patients with juvenile rheumatoid arthritis (JRA), for the purpose of improving differential diagnosis and monitoring disease activity. Methods. In a 2-year prospective study, serum levels of interleukin-lp (IL-