The importance of the cellular pharmacokinetics of cytarabine triphosphate (ara-CTP) with regard to therapeutic efficacy is well established. In vitro and in vivo monitoring of pharmacokinetic parameters of leukemic blast cells were initiated in order to contribute to the pharmacological basis of op
✦ LIBER ✦
Cytokine-Driven Differentiation of Blasts from Patients with Acute Myelogenous and Lymphoblastic Leukemia into Dendritic Cells
✍ Scribed by T. Köhler; R. Plettig; W. Wetzstein; M. Schmitz; M. Ritter; B. Mohr; U. Schaekel; G. Ehninger; M. Bornhäuser
- Book ID
- 119923422
- Publisher
- AlphaMed Press
- Year
- 2000
- Tongue
- English
- Weight
- 102 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1066-5099
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## Abstract Eight patients with acute lymphosarcoma cell leukemia or acute lymphoblastic leukemia received infusions of plasma containing a lymphotoxic factor. The lymphotoxic factor induced a transient fall in the number of “blast” cell forms in the peripheral blood in six of the eight patients bu