Cytokeratins as molecular markers in the evaluation of the precise differentiation stage of human gingival epithelium reconstituted in vitro

Bronchial micronuclei as a marker of an

Bronchial micronuclei as a marker of an early stage of carcinogenesis in the human tracheobronchial epithelium

✍ Scott M. Lippman; Edward J. Peters; Michael J. Wargovich; Alexander N. Stadnyk; 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 515 KB

## Abstract In the bronchial epithelium, smoking initiates a multistep process that first appears histologically as premalignant squamous metaplasia/dysplasia, a biological predecessor of squamous‐cell lung cancer. Reflecting chromosomal damage from a carcinogenic insult, micronuclei may reveal ear