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Cytogenetics of two cases of TNSGCT with different histological components: Jannie van Echten, Willem E. de Graaff, Bauke de Jong, J. Wolter Oosterhuis, Janneke Wiersema, Heimen Schraffordt Koops, Dirk Th. Sleijfer. From the University and University hospital of Groningen and the DdHK Rotterdam, The Netherlands


Book ID
119105677
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
102 KB
Volume
63
Category
Article
ISSN
0165-4608

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Malignant transformation may be caused by gene deregulation resulting from specific chromosomal rearrangements, by amplification, by mutations in proto-oncogenes, by loss of tumor suppressor genes, or a combination of these. We investigated the role of numerical and structural chromosomal abnormalit