✦ LIBER ✦

Cytogenetics of sacral chordoma

✍ Scribed by Joanne M. DeBoer; James R. Neff; Julia A. Bridge

Book ID: 119105538
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 445 KB
Volume: 64
Category: Article
ISSN: 0165-4608
DOI: 10.1016/0165-4608(92)90332-3

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Background and Objectives: Microsatellite instability (MIN) is an indirect marker of globally defective DNA mismatch repair in the neoplastic cells of cancer patients. Chordomas are rare, primary skeletal malignancies for which few characteristic molecular genetic markers have been identified. Is MI