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Cytogenetics and molecular cytogenetics in multiple myeloma

✍ Scribed by Peter Liebisch; Hartmut Döhner


Book ID
116428885
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
263 KB
Volume
42
Category
Article
ISSN
0959-8049

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Comparative genomic hybridization (CGH) was used to identify recurrent regions of DNA sequence loss and gain in 21 multiple myeloma (MM) and plasma cell leukemia (PCL) primary tumor specimens and cell lines. Multiple regions of non-random sequence loss and gain were observed in 8/8 primary advanced